Aldehyde dehydrogenases inhibition eradicates leukemia stem cells while sparing normal progenitors

The vast majority of patients with acute myeloid leukemia (AML) achieve complete remission (CR) after standard induction chemotherapy. However, the majority subsequently relapse and die of the disease. A leukemia stem cell (LSC) paradigm has been invoked to explain this failure of CR to reliably tra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Cancer J
Main Authors: Venton, G, Pérez-Alea, M, Baier, C, Fournet, G, Quash, G, Labiad, Y, Martin, G, Sanderson, F, Poullin, P, Suchon, P, Farnault, L, Nguyen, C, Brunet, C, Ceylan, I, Costello, R T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056970/
https://ncbi.nlm.nih.gov/pubmed/27611922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bcj.2016.78
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados