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N,N-diethylaminobenzaldehyde targets aldehyde dehydrogenase to eradicate human pancreatic cancer cells

Pancreatic cancer is a common cause of worldwide cancer-related mortality with a poor 5-year survival rate. Aldehyde dehydrogenase (ALDH) activity is a possible marker for malignant stem cells in solid organ systems, including the pancreas, and N,N-diethylaminobenzaldehyde (DEAB) is able to inhibit...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Wang, Wenwen, Zheng, Shiya, He, Haiju, Ge, Hao, Saeed, Borhan R.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7296292/
https://ncbi.nlm.nih.gov/pubmed/32550888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8691
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