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Effects of Fibrinogen Concentrate on Thrombin Generation, Thromboelastometry Parameters, and Laboratory Coagulation Testing in a 24-Hour Porcine Trauma Model

INTRODUCTION: In a 24-hour porcine model of liver injury, we showed that fibrinogen supplementation does not downregulate endogenous fibrinogen synthesis. Here we report data from the same study showing the impact of fibrinogen on coagulation variables. MATERIALS AND METHODS: Coagulopathy was induce...

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Dettagli Bibliografici
Pubblicato in:Clin Appl Thromb Hemost
Autori principali: Zentai, Christian, Solomon, Cristina, van der Meijden, Paola E. J., Spronk, Henri M. H., Schnabel, Jonas, Rossaint, Rolf, Grottke, Oliver
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056597/
https://ncbi.nlm.nih.gov/pubmed/25948634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1076029615584662
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