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Thrombin Generation Capacity of Prothrombin Complex Concentrate in an In Vitro Dilutional Model

BACKGROUND: The use of PCC for the treatment of trauma-induced coagulopathy potentially increase the risk of thromboembolism and disseminated intravascular coagulation, which is addressed to an imbalance of both pro- and anticoagulants. As PCCs differ in composition, we used an in vitro dilutional a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Grottke, Oliver, Rossaint, Rolf, Henskens, Yvonne, van Oerle, Rene, ten Cate, Hugo, Spronk, Henri M. H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656958/
https://ncbi.nlm.nih.gov/pubmed/23696866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064100
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