Inhibition of Ileal Bile Acid Uptake Protects Against Non-alcoholic Fatty Liver Disease in High Fat Diet-fed Mice

Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the Western world, and safe and effective therapies are needed. Bile acids (BAs) and their receptors (including the nuclear receptor for BAs, FXR) play integral roles in regulating whole body metabolism and hepatic...

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Publicado no:Sci Transl Med
Main Authors: Rao, Anuradha, Kosters, Astrid, Mells, Jamie E., Zhang, Wujuan, Setchell, Kenneth D. R., Amanso, Angelica M., Wynn, Grace M., Xu, Tianlei, Keller, Brad T., Yin, Hong, Banton, Sophia, Jones, Dean P., Wu, Hao, Dawson, Paul A., Karpen, Saul J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056562/
https://ncbi.nlm.nih.gov/pubmed/27655848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaf4823
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