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p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPARα

Fasting is a physiological stress that elicits well-known metabolic adaptations, however, little is known about the role of stress-responsive tumor suppressors in fasting. Here, we have examined the expression of several tumor suppressors upon fasting in mice. Interestingly, p21 mRNA is uniquely ind...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Lopez-Guadamillas, Elena, Fernandez-Marcos, Pablo J., Pantoja, Cristina, Muñoz-Martin, Maribel, Martínez, Dolores, Gómez-López, Gonzalo, Campos-Olivas, Ramón, Valverde, Angela M., Serrano, Manuel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056372/
https://ncbi.nlm.nih.gov/pubmed/27721423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34542
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