Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment

Overactive mitochondrial fission was shown to promote cell transformation and tumor growth. It remains elusive how mitochondrial quality is regulated in such conditions. Here, we show that upregulation of mitochondrial fission protein, dynamin related protein-1 (Drp1), was accompanied with increased...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zou, Peng, Liu, Longhua, Zheng, Louise D., Payne, Kyle K., Manjili, Masoud H., Idowu, Michael O., Zhang, Jinfeng, Schmelz, Eva M., Cheng, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056295/
https://ncbi.nlm.nih.gov/pubmed/27746856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4085727
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