Tumor escape and progression of HER-2/neu negative breast cancer under immune pressure

BACKGROUND: Emerging data from pre-clinical and clinical studies suggest that HER-2/neu-specific T cell responses could induce HER-2/neu antigen loss in the tumor cells. These data suggest that patients with HER-2/neu negative breast cancer might have had HER-2/neu positive premalignant lesions in t...

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Autori principali: Kmieciak, Maciej, Payne, Kyle K, Idowu, Michael O, Grimes, Margaret M, Graham, Laura, Ascierto, Maria-Libera, Wang, Ena, Wang, Xiang-Yang, Bear, Harry D, Manjili, Masoud H
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076247/
https://ncbi.nlm.nih.gov/pubmed/21453513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-35
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