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IFN-γ Rα Is a Key Determinant of CD8+ T Cell-Mediated Tumor Elimination or Tumor Escape and Relapse in FVB Mouse

During the past decade, the dual function of the immune system in tumor inhibition and tumor progression has become appreciated. We have previously reported that neu-specific T cells can induce rejection of neu positive mouse mammary carcinoma (MMC) and also facilitate tumor relapse by inducing neu...

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Detalhes bibliográficos
Main Authors: Kmieciak, Maciej, Payne, Kyle K., Wang, Xiang-Yang, Manjili, Masoud H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855782/
https://ncbi.nlm.nih.gov/pubmed/24324806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082544
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