Загрузка...
mTORC1–S6K1 inhibition or mTORC2 activation improves hippocampal synaptic plasticity and learning in Angelman syndrome mice
Emerging evidence is implicating abnormal activation of the mechanistic target of rapamycin (mTOR) pathway in several monogenetic neuropsychiatric disorders, including Angelman syndrome (AS), which is caused by deficiency in maternally inherited UBE3A. Using an AS mouse model, we show that semi-chro...
Сохранить в:
| Опубликовано в: : | Cell Mol Life Sci |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer International Publishing
2016
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056144/ https://ncbi.nlm.nih.gov/pubmed/27173058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-016-2269-z |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|