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Strain analysis of protein structures and low dimensionality of mechanical allosteric couplings

In many proteins, especially allosteric proteins that communicate regulatory states from allosteric to active sites, structural deformations are functionally important. To understand these deformations, dynamical experiments are ideal but challenging. Using static structural information, although mo...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Mitchell, Michael R., Tlusty, Tsvi, Leibler, Stanislas
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056043/
https://ncbi.nlm.nih.gov/pubmed/27655887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1609462113
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