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Lipid-induced mTOR activation in rat skeletal muscle reversed by exercise and 5′-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside

The serine/threonine protein kinase, mammalian target of rapamycin (mTOR) is regulated by insulin and nutrient availability and has been proposed to play a central role as a nutrient sensor in skeletal muscle. mTOR associates with its binding partners, raptor and rictor, to form two structurally and...

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Dettagli Bibliografici
Pubblicato in:J Endocrinol
Autori principali: Rivas, Donato A, Yaspelkis, Ben B, Hawley, John A, Lessard, Sarah J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055835/
https://ncbi.nlm.nih.gov/pubmed/19574345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-09-0202
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