Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside

BACKGROUND: Insulin-induced microvascular recruitment is important for optimal muscle glucose uptake. 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR, an activator of AMP-activated protein kinase), can also induce microvascular recruitment, at doses that do not acutely activate glucose tr...

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Dades bibliogràfiques
Publicat a:Cardiovasc Diabetol
Autors principals: Bradley, Eloise A, Zhang, Lei, Genders, Amanda J, Richards, Stephen M, Rattigan, Stephen, Keske, Michelle A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509722/
https://ncbi.nlm.nih.gov/pubmed/26194188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0251-y
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