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LDL-Lipids from patients with hypercholesterolaemia and Alzheimer’s disease are inflammatory to microvascular endothelial cells: Mitigation by statin intervention

Elevated LDL concentration in mid-life increases the risk of developing Alzheimer’s disease (AD) in later life. Increased oxidative modification (oxLDL) and nitration is observed during dementia and hypercholesterolemia. We investigated the hypothesis that statin intervention in mid-life mitigates t...

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書目詳細資料
發表在:Clin Sci (Lond)
Main Authors: Dias, H. K. I., Brown, C. L. R., Polidori, M. C., Lip, G.Y.H., Griffiths, H.R.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055810/
https://ncbi.nlm.nih.gov/pubmed/26399707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20150351
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