LDL-Lipids from patients with hypercholesterolaemia and Alzheimer’s disease are inflammatory to microvascular endothelial cells: Mitigation by statin intervention

Elevated LDL concentration in mid-life increases the risk of developing Alzheimer’s disease (AD) in later life. Increased oxidative modification (oxLDL) and nitration is observed during dementia and hypercholesterolemia. We investigated the hypothesis that statin intervention in mid-life mitigates t...

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Publicado en:Clin Sci (Lond)
Main Authors: Dias, H. K. I., Brown, C. L. R., Polidori, M. C., Lip, G.Y.H., Griffiths, H.R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055810/
https://ncbi.nlm.nih.gov/pubmed/26399707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20150351
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