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Evidence that Oxidative Stress Induces spxA2 Transcription in Bacillus anthracis Sterne through a Mechanism Requiring SpxA1 and Positive Autoregulation

Bacillus anthracis possesses two paralogs of the transcriptional regulator, Spx. SpxA1 and SpxA2 interact with RNA polymerase (RNAP) to activate the transcription of genes implicated in the prevention and alleviation of oxidative protein damage. The spxA2 gene is highly upregulated in infected macro...

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Bibliografske podrobnosti
izdano v:J Bacteriol
Main Authors: Barendt, Skye, Birch, Cierra, Mbengi, Lea, Zuber, Peter
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055595/
https://ncbi.nlm.nih.gov/pubmed/27501985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00512-16
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