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Evidence that Oxidative Stress Induces spxA2 Transcription in Bacillus anthracis Sterne through a Mechanism Requiring SpxA1 and Positive Autoregulation

Bacillus anthracis possesses two paralogs of the transcriptional regulator, Spx. SpxA1 and SpxA2 interact with RNA polymerase (RNAP) to activate the transcription of genes implicated in the prevention and alleviation of oxidative protein damage. The spxA2 gene is highly upregulated in infected macro...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Barendt, Skye, Birch, Cierra, Mbengi, Lea, Zuber, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055595/
https://ncbi.nlm.nih.gov/pubmed/27501985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00512-16
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