Evidence that Oxidative Stress Induces spxA2 Transcription in Bacillus anthracis Sterne through a Mechanism Requiring SpxA1 and Positive Autoregulation

Bacillus anthracis possesses two paralogs of the transcriptional regulator, Spx. SpxA1 and SpxA2 interact with RNA polymerase (RNAP) to activate the transcription of genes implicated in the prevention and alleviation of oxidative protein damage. The spxA2 gene is highly upregulated in infected macro...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Barendt, Skye, Birch, Cierra, Mbengi, Lea, Zuber, Peter
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055595/
https://ncbi.nlm.nih.gov/pubmed/27501985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00512-16
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