Evidence that Oxidative Stress Induces spxA2 Transcription in Bacillus anthracis Sterne through a Mechanism Requiring SpxA1 and Positive Autoregulation

Bacillus anthracis possesses two paralogs of the transcriptional regulator, Spx. SpxA1 and SpxA2 interact with RNA polymerase (RNAP) to activate the transcription of genes implicated in the prevention and alleviation of oxidative protein damage. The spxA2 gene is highly upregulated in infected macro...

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Vydáno v:J Bacteriol
Hlavní autoři: Barendt, Skye, Birch, Cierra, Mbengi, Lea, Zuber, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055595/
https://ncbi.nlm.nih.gov/pubmed/27501985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00512-16
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