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Inactivation of the spxA1 or spxA2 gene of Streptococcus mutans decreases virulence in the rat caries model

In oral biofilms, the major environmental challenges encountered by Streptococcus mutans are acid and oxidative stresses. Previously, we showed that the transcriptional regulators SpxA1 and SpxA2 are involved in general stress survival of S. mutans with SpxA1 playing a primary role in activation of...

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Bibliografiska uppgifter
I publikationen:Mol Oral Microbiol
Huvudupphovsmän: Galvão, Lívia C.C., Rosalen, Pedro L., Rivera-Ramos, Isamar, Franco, Gilson C.N., Kajfasz, Jessica K, Abranches, Jacqueline, Bueno-Silva, Bruno, Koo, Hyun, Lemos, José A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045749/
https://ncbi.nlm.nih.gov/pubmed/27037617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/omi.12160
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