Effect of Glycosylation on an Immunodominant Region in the V1V2 Variable Domain of the HIV-1 Envelope gp120 Protein

Heavy glycosylation of the envelope (Env) surface subunit, gp120, is a key adaptation of HIV-1; however, the precise effects of glycosylation on the folding, conformation and dynamics of this protein are poorly understood. Here we explore the patterns of HIV-1 Env gp120 glycosylation, and particular...

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Gepubliceerd in:PLoS Comput Biol
Hoofdauteurs: Tian, Jianhui, López, Cesar A., Derdeyn, Cynthia A., Jones, Morris S., Pinter, Abraham, Korber, Bette, Gnanakaran, S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055340/
https://ncbi.nlm.nih.gov/pubmed/27716795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005094
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