Rapid disintegrating tablets of simvastatin dispersions in polyoxyethylene–polypropylene block copolymer for maximized disintegration and dissolution

The objective of this research was to improve the dissolution of simvastatin and to incorporate it in rapid disintegrating tablets (RDTs) with an optimized disintegration and dissolution characteristics. Polyoxyethylene–polypropylene block copolymer (poloxamer 188) was employed as a hydrophilic carr...

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Vydáno v:Drug Des Devel Ther
Hlavní autoři: Balata, Gehan F, Zidan, Ahmad S, Abourehab, Mohamad AS, Essa, Ebtessam A
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2016
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055116/
https://ncbi.nlm.nih.gov/pubmed/27757012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S114724
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