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Rapid disintegrating tablets of simvastatin dispersions in polyoxyethylene–polypropylene block copolymer for maximized disintegration and dissolution

The objective of this research was to improve the dissolution of simvastatin and to incorporate it in rapid disintegrating tablets (RDTs) with an optimized disintegration and dissolution characteristics. Polyoxyethylene–polypropylene block copolymer (poloxamer 188) was employed as a hydrophilic carr...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Drug Des Devel Ther
Päätekijät: Balata, Gehan F, Zidan, Ahmad S, Abourehab, Mohamad AS, Essa, Ebtessam A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Dove Medical Press 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055116/
https://ncbi.nlm.nih.gov/pubmed/27757012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S114724
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