Defining antigen-specific plasmablast and memory B cell subsets in blood following viral infection and vaccination of humans

Antigen-specific B cells bifurcate into antibody secreting cells (ASC) and memory B cells after infection or vaccination. ASCs or plasmablasts have been extensively studied in humans but less is known about B cells that get activated but do not differentiate into early plasmablasts. Here, we define...

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Pubblicato in:Nat Immunol
Autori principali: Ellebedy, Ali H., Jackson, Katherine J.L., Kissick, Haydn T., Nakaya, Helder I., Davis, Carl W., Roskin, Krishna M., McElroy, Anita K., Oshansky, Christine M., Elbein, Rivka, Thomas, Shine, Lyon, George M., Spiropoulou, Christina F., Mehta, Aneesh K., Thomas, Paul G., Boyd, Scott D., Ahmed, Rafi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054979/
https://ncbi.nlm.nih.gov/pubmed/27525369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3533
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