Defining antigen-specific plasmablast and memory B cell subsets in blood following viral infection and vaccination of humans

Antigen-specific B cells bifurcate into antibody secreting cells (ASC) and memory B cells after infection or vaccination. ASCs or plasmablasts have been extensively studied in humans but less is known about B cells that get activated but do not differentiate into early plasmablasts. Here, we define...

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Publicado no:Nat Immunol
Main Authors: Ellebedy, Ali H., Jackson, Katherine J.L., Kissick, Haydn T., Nakaya, Helder I., Davis, Carl W., Roskin, Krishna M., McElroy, Anita K., Oshansky, Christine M., Elbein, Rivka, Thomas, Shine, Lyon, George M., Spiropoulou, Christina F., Mehta, Aneesh K., Thomas, Paul G., Boyd, Scott D., Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054979/
https://ncbi.nlm.nih.gov/pubmed/27525369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3533
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