Human Ebola virus infection results in substantial immune activation

Four Ebola patients received care at Emory University Hospital, presenting a unique opportunity to examine the cellular immune responses during acute Ebola virus infection. We found striking activation of both B and T cells in all four patients. Plasmablast frequencies were 10–50% of B cells, compar...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: McElroy, Anita K., Akondy, Rama S., Davis, Carl W., Ellebedy, Ali H., Mehta, Aneesh K., Kraft, Colleen S., Lyon, G. Marshall, Ribner, Bruce S., Varkey, Jay, Sidney, John, Sette, Alessandro, Campbell, Shelley, Ströher, Ute, Damon, Inger, Nichol, Stuart T., Spiropoulou, Christina F., Ahmed, Rafi
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403189/
https://ncbi.nlm.nih.gov/pubmed/25775592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502619112
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