Human Ebola virus infection results in substantial immune activation

Four Ebola patients received care at Emory University Hospital, presenting a unique opportunity to examine the cellular immune responses during acute Ebola virus infection. We found striking activation of both B and T cells in all four patients. Plasmablast frequencies were 10–50% of B cells, compar...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: McElroy, Anita K., Akondy, Rama S., Davis, Carl W., Ellebedy, Ali H., Mehta, Aneesh K., Kraft, Colleen S., Lyon, G. Marshall, Ribner, Bruce S., Varkey, Jay, Sidney, John, Sette, Alessandro, Campbell, Shelley, Ströher, Ute, Damon, Inger, Nichol, Stuart T., Spiropoulou, Christina F., Ahmed, Rafi
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403189/
https://ncbi.nlm.nih.gov/pubmed/25775592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502619112
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