Human Ebola virus infection results in substantial immune activation

Four Ebola patients received care at Emory University Hospital, presenting a unique opportunity to examine the cellular immune responses during acute Ebola virus infection. We found striking activation of both B and T cells in all four patients. Plasmablast frequencies were 10–50% of B cells, compar...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: McElroy, Anita K., Akondy, Rama S., Davis, Carl W., Ellebedy, Ali H., Mehta, Aneesh K., Kraft, Colleen S., Lyon, G. Marshall, Ribner, Bruce S., Varkey, Jay, Sidney, John, Sette, Alessandro, Campbell, Shelley, Ströher, Ute, Damon, Inger, Nichol, Stuart T., Spiropoulou, Christina F., Ahmed, Rafi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2015
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403189/
https://ncbi.nlm.nih.gov/pubmed/25775592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1502619112
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