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Autophagy Deficiency in Macrophages Enhances NLRP3 Inflammasome Activity and Chronic Lung Disease Following Silica Exposure

Autophagy is an important metabolic mechanism that can promote cellular survival following injury. The specific contribution of autophagy to silica-induced inflammation and disease is not known. The objective of these studies was to determine the effects of silica exposure on the autophagic pathway...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Toxicol Appl Pharmacol
Päätekijät: Jessop, Forrest, Hamilton, Raymond F., Rhoderick, Joseph F., Shaw, Pamela K, Holian, Andrij
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054752/
https://ncbi.nlm.nih.gov/pubmed/27594529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.08.029
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