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Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO

MARCO is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). Previously, it was shown that mice null for MARCO have a greater inflammatory response to silica, but the mechanism was not described. The aim of this study was to determine the...

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Main Authors: Biswas, Rupa, Hamilton, Raymond F., Holian, Andrij
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099041/
https://ncbi.nlm.nih.gov/pubmed/25054161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/304180
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