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Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO

MARCO is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). Previously, it was shown that mice null for MARCO have a greater inflammatory response to silica, but the mechanism was not described. The aim of this study was to determine the...

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Detalhes bibliográficos
Main Authors: Biswas, Rupa, Hamilton, Raymond F., Holian, Andrij
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099041/
https://ncbi.nlm.nih.gov/pubmed/25054161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/304180
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