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Role of Lysosomes in Silica-Induced Inflammasome Activation and Inflammation in Absence of MARCO

MARCO is the predominant scavenger receptor for recognition and binding of silica particles by alveolar macrophages (AM). Previously, it was shown that mice null for MARCO have a greater inflammatory response to silica, but the mechanism was not described. The aim of this study was to determine the...

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書目詳細資料
Main Authors: Biswas, Rupa, Hamilton, Raymond F., Holian, Andrij
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4099041/
https://ncbi.nlm.nih.gov/pubmed/25054161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/304180
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