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Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G

Parkinson’s disease is one of the most common neurodegenerative disorders and several mutations in different genes have been identified to contribute to the disease. A loss of function parkin RING1 domain mutant (C289G) is associated with autosomal-recessive juvenile-onset Parkinsonism (AR-JP) and d...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Kakkar, Vaishali, Kuiper, E. F. Elsiena, Pandey, Abhinav, Braakman, Ineke, Kampinga, Harm H.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054386/
https://ncbi.nlm.nih.gov/pubmed/27713507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34830
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