The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo

A phase 2 clinical trial investigating the efficacy and safety of AS602801, a newly developed JNK inhibitor, in the treatment of inflammatory endometriosis is complete. We are now examining whether AS602801 acts against human cancer cells in vitro and in vivo. In vitro, AS602801 exhibited cytotoxici...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Okada, Masashi, Kuramoto, Kenta, Takeda, Hiroyuki, Watarai, Hikaru, Sakaki, Hirotsugu, Seino, Shizuka, Seino, Manabu, Suzuki, Shuhei, Kitanaka, Chifumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053629/
https://ncbi.nlm.nih.gov/pubmed/27027242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8395
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