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JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells

Chemoresistance associated with cancer stem cells (CSCs), which is now being held responsible for the pervasive therapy resistance of pancreatic cancer, poses a major challenge to the successful management of this devastating malignancy. However, the molecular mechanism underlying the marked chemore...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Suzuki, Shuhei, Okada, Masashi, Shibuya, Keita, Seino, Manabu, Sato, Atsushi, Takeda, Hiroyuki, Seino, Shizuka, Yoshioka, Takashi, Kitanaka, Chifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381607/
https://ncbi.nlm.nih.gov/pubmed/25473894
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