JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells

Chemoresistance associated with cancer stem cells (CSCs), which is now being held responsible for the pervasive therapy resistance of pancreatic cancer, poses a major challenge to the successful management of this devastating malignancy. However, the molecular mechanism underlying the marked chemore...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Suzuki, Shuhei, Okada, Masashi, Shibuya, Keita, Seino, Manabu, Sato, Atsushi, Takeda, Hiroyuki, Seino, Shizuka, Yoshioka, Takashi, Kitanaka, Chifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381607/
https://ncbi.nlm.nih.gov/pubmed/25473894
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