LIM kinase/cofilin dysregulation promotes macrothrombocytopenia in severe von Willebrand disease-type 2B

von Willebrand disease type 2B (VWD-type 2B) is characterized by gain-of-function mutations of von Willebrand factor (vWF) that enhance its binding to platelet glycoprotein Ibα and alter the protein’s multimeric structure. Patients with VWD-type 2B display variable extents of bleeding associated wit...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Kauskot, Alexandre, Poirault-Chassac, Sonia, Adam, Frédéric, Muczynski, Vincent, Aymé, Gabriel, Casari, Caterina, Bordet, Jean-Claude, Soukaseum, Christelle, Rothschild, Chantal, Proulle, Valérie, Pietrzyk-Nivau, Audrey, Berrou, Eliane, Christophe, Olivier D., Rosa, Jean-Philippe, Lenting, Peter J., Bryckaert, Marijke, Denis, Cécile V., Baruch, Dominique
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2016
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053155/
https://ncbi.nlm.nih.gov/pubmed/27734030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88643
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料