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Acetylation Mimics Within a Single Nucleosome Alter Local DNA Accessibility In Compacted Nucleosome Arrays

The activation of a silent gene locus is thought to involve pioneering transcription factors that initiate changes in the local chromatin structure to increase promoter accessibility and binding of downstream effectors. To better understand the molecular requirements for the first steps of locus act...

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Publicat a:Sci Rep
Autors principals: Mishra, Laxmi N., Pepenella, Sharon, Rogge, Ryan, Hansen, Jeffrey C., Hayes, Jeffrey J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052607/
https://ncbi.nlm.nih.gov/pubmed/27708426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34808
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