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Acetylation Mimics Within a Single Nucleosome Alter Local DNA Accessibility In Compacted Nucleosome Arrays

The activation of a silent gene locus is thought to involve pioneering transcription factors that initiate changes in the local chromatin structure to increase promoter accessibility and binding of downstream effectors. To better understand the molecular requirements for the first steps of locus act...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mishra, Laxmi N., Pepenella, Sharon, Rogge, Ryan, Hansen, Jeffrey C., Hayes, Jeffrey J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052607/
https://ncbi.nlm.nih.gov/pubmed/27708426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34808
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