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Acetylation Mimics Within a Single Nucleosome Alter Local DNA Accessibility In Compacted Nucleosome Arrays

The activation of a silent gene locus is thought to involve pioneering transcription factors that initiate changes in the local chromatin structure to increase promoter accessibility and binding of downstream effectors. To better understand the molecular requirements for the first steps of locus act...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Mishra, Laxmi N., Pepenella, Sharon, Rogge, Ryan, Hansen, Jeffrey C., Hayes, Jeffrey J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052607/
https://ncbi.nlm.nih.gov/pubmed/27708426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34808
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