Sorafenib exerts an anti-keloid activity by antagonizing TGF-β/Smad and MAPK/ERK signaling pathways

ABSTRACT: Keloid disease is characterized by hyperproliferation of responsive fibroblasts with vigorously continuous synthesis of extracellular matrix (ECM) components. Although the process by which keloids develop is poorly understood, most theories of the etiology are referred to fibroblast dysfun...

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Bibliografiske detaljer
Udgivet i:J Mol Med (Berl)
Main Authors: Wang, Wenbo, Qu, Miao, Xu, Lan, Wu, Xiaoli, Gao, Zhen, Gu, Tingyu, Zhang, Wenjie, Ding, Xiaoyan, Liu, Wei, Chen, Yue-Lei
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052317/
https://ncbi.nlm.nih.gov/pubmed/27339758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-016-1430-3
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