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B Cell-Derived IL-15 Enhances CD8 T Cell Cytotoxicity and Is Increased in Multiple Sclerosis Patients

Multiple lines of evidence suggest that CD8 T cells contribute to the pathogenesis of multiple sclerosis (MS). However, the sources and involvement of cytokines such as IL-15 in activating these cells is still unresolved. To investigate the role of IL-15 in enhancing the activation of CD8 T cells in...

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Bibliographische Detailangaben
Veröffentlicht in:J Immunol
Hauptverfasser: Schneider, Raphael, Mohebiany, Alma Nazlie, Ifergan, Igal, Beauseigle, Diane, Duquette, Pierre, Prat, Alexandre, Arbour, Nathalie
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052068/
https://ncbi.nlm.nih.gov/pubmed/21911607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100885
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