Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis

<p>Abstract</p> <p>Background</p> <p>Multiple sclerosis (MS), an inflammatory disease of the central nervous system (CNS), is characterized by blood-brain barrier (BBB) disruption and massive infiltration of activated immune cells. Engagement of programmed cell death-1...

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Auteurs principaux: Pittet Camille L, Newcombe Jia, Prat Alexandre, Arbour Nathalie
Format: Artigo
Langue:Inglês
Publié: BMC 2011-11-01
Collection:Journal of Neuroinflammation
Sujets:
blood-brain barrier
CD8 T cells
endothelial cells
PD-L1
PD-L2
B7 molecules
Accès en ligne:http://www.jneuroinflammation.com/content/8/1/155
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