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Contribution of CD8 T lymphocytes to the immuno-pathogenesis of multiple sclerosis and its animal models

Multiple sclerosis (MS) is an inflammatory disease of the central nervous system (CNS) characterized by multi-focal demyelination, axonal loss, and immune cell infiltration. Numerous immune mediators are detected within MS lesions, including CD4(+) and CD8(+) T lymphocytes suggesting that they parti...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Mars, Lennart T., Saikali, Philippe, Liblau, Roland S., Arbour, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052066/
https://ncbi.nlm.nih.gov/pubmed/20637863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2010.07.006
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