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Fibrinogen blocks the autoactivation and thrombin-mediated activation of factor XI on dextran sulfate.

The intrinsic pathway of blood coagulation is activated when factor XIa, one of the three contact-system enzymes, is generated and then activates factor IX. Factor XI has been shown to be efficiently activated in vitro by surface-bound factor XIIa after factor XI is transported to the surface by its...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Scott, C F, Colman, R W
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC50515/
https://ncbi.nlm.nih.gov/pubmed/1454798
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