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SMARCAL1 Resolves Replication Stress at ALT Telomeres
Cancer cells overcome replicative senescence by exploiting mechanisms of telomere elongation, a process often accomplished by reactivation of the enzyme telomerase. However, a subset of cancer cells lack telomerase activity and rely on the alternative lengthening of telomeres (ALT) pathway, a recomb...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5051350/ https://ncbi.nlm.nih.gov/pubmed/26832416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.01.011 |
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