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PARP1 Differentially Interacts with Promoter region of DUX4 Gene in FSHD Myoblasts

OBJECTIVE: The goal of the study is to identity proteins, which interact with the promoter region of double homeobox protein 4 (DUX4) gene known to be causative for the autosomal dominant disorder Facioscapulohumeral Muscular Dystrophy (FSHD). METHODS: We performed a DNA pull down assay coupled with...

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Bibliografski detalji
Izdano u:J Genet Syndr Gene Ther
Glavni autori: Sharma, Vishakha, Pandey, Sachchida Nand, Khawaja, Hunain, Brown, Kristy J, Hathout, Yetrib, Chen, Yi-Wen
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5051271/
https://ncbi.nlm.nih.gov/pubmed/27722032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2157-7412.1000303
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