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An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates

A licensed vaccine against Ebola virus (EBOV) remains unavailable, despite >11 000 deaths from the 2014–2016 outbreak of EBOV disease in West Africa. Past studies have shown that recombinant vaccine viruses expressing EBOV glycoprotein (GP) are able to protect nonhuman primates (NHPs) from a leth...

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書目詳細資料
發表在:J Infect Dis
Main Authors: Wu, Shipo, Kroeker, Andrea, Wong, Gary, He, Shihua, Hou, Lihua, Audet, Jonathan, Wei, Haiyan, Zhang, Zhe, Fernando, Lisa, Soule, Geoff, Tran, Kaylie, Bi, Shengli, Zhu, Tao, Yu, Xuefeng, Chen, Wei, Qiu, Xiangguo
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050474/
https://ncbi.nlm.nih.gov/pubmed/27493239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw250
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