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An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates
A licensed vaccine against Ebola virus (EBOV) remains unavailable, despite >11 000 deaths from the 2014–2016 outbreak of EBOV disease in West Africa. Past studies have shown that recombinant vaccine viruses expressing EBOV glycoprotein (GP) are able to protect nonhuman primates (NHPs) from a leth...
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發表在: | J Infect Dis |
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Main Authors: | , , , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Oxford University Press
2016
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050474/ https://ncbi.nlm.nih.gov/pubmed/27493239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw250 |
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