An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates

A licensed vaccine against Ebola virus (EBOV) remains unavailable, despite >11 000 deaths from the 2014–2016 outbreak of EBOV disease in West Africa. Past studies have shown that recombinant vaccine viruses expressing EBOV glycoprotein (GP) are able to protect nonhuman primates (NHPs) from a leth...

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Foilsithe in:J Infect Dis
Main Authors: Wu, Shipo, Kroeker, Andrea, Wong, Gary, He, Shihua, Hou, Lihua, Audet, Jonathan, Wei, Haiyan, Zhang, Zhe, Fernando, Lisa, Soule, Geoff, Tran, Kaylie, Bi, Shengli, Zhu, Tao, Yu, Xuefeng, Chen, Wei, Qiu, Xiangguo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2016
Ábhair:
Ebola Outbreak in West Africa
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050474/
https://ncbi.nlm.nih.gov/pubmed/27493239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw250
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