An Adenovirus Vaccine Expressing Ebola Virus Variant Makona Glycoprotein Is Efficacious in Guinea Pigs and Nonhuman Primates

A licensed vaccine against Ebola virus (EBOV) remains unavailable, despite >11 000 deaths from the 2014–2016 outbreak of EBOV disease in West Africa. Past studies have shown that recombinant vaccine viruses expressing EBOV glycoprotein (GP) are able to protect nonhuman primates (NHPs) from a leth...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Infect Dis
Prif Awduron: Wu, Shipo, Kroeker, Andrea, Wong, Gary, He, Shihua, Hou, Lihua, Audet, Jonathan, Wei, Haiyan, Zhang, Zhe, Fernando, Lisa, Soule, Geoff, Tran, Kaylie, Bi, Shengli, Zhu, Tao, Yu, Xuefeng, Chen, Wei, Qiu, Xiangguo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2016
Pynciau:
Ebola Outbreak in West Africa
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050474/
https://ncbi.nlm.nih.gov/pubmed/27493239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw250
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