Antiangiogenic therapy using endostatin increases the number of ALDH+ lung cancer stem cells by generating intratumor hypoxia

Antiangiogenic therapy is becoming a promising option for cancer treatment. However, many investigations have recently indicated that these therapies may have limited efficacy, and the cancers in most patients eventually develop resistance to these therapies. There is considerable recently acquired...

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Published in:Sci Rep
Main Authors: Yu, Yang, Wang, Yu-yi, Wang, Yi-qin, Wang, Xia, Liu, Yan-Yang, Wang, Jian-Tao, Du, Chi, Wang, Li, Li, Mei, Luo, Feng, Jiang, Ming
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050420/
https://ncbi.nlm.nih.gov/pubmed/27703219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34239
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