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E-selectin is required for the antiangiogenic activity of endostatin

Endostatin, a 20-kDa fragment of collagen XVIII, is a potent angiogenesis inhibitor. E-selectin, an inducible leukocyte adhesion molecule specifically expressed by endothelial cells, has also been implicated in angiogenesis. By using in vivo, ex vivo, and in vitro angiogenic assays, we investigated...

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Détails bibliographiques
Auteurs principaux: Yu, Ying, Moulton, Karen S., Khan, Mohamed K., Vineberg, Sabrina, Boye, Eileen, Davis, Vannessa M., O'Donnell, Peter E., Bischoff, Joyce, Milstone, David S.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2004
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC419547/
https://ncbi.nlm.nih.gov/pubmed/15148373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0402551101
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