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Antiangiogenic Gene Therapy of Cancer Utilizing a Recombinant Adenovirus to Elevate Systemic Endostatin Levels in Mice

Gene therapy represents a possible alternative to the chronic delivery of recombinant antiangiogenic proteins to cancer patients. Inducing normal host tissues to produce high circulating levels of these proteins may be more effective than targeting antiangiogenic genes to tumor tissue specifically....

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Autors principals: Feldman, Andrew L., Restifo, Nicholas P., Alexander, H. Richard, Bartlett, David L., Hwu, Patrick, Seth, Prem, Libutti, Steven K.
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2247479/
https://ncbi.nlm.nih.gov/pubmed/10749112
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