Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis

Functionally compromised neutrophils contribute to adverse clinical outcomes in patients with severe inflammation and injury such as colitis and sepsis. However, the ontogeny of dysfunctional neutrophil during septic colitis remain poorly understood. We report that the dysfunctional neutrophil may b...

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Publicado no:Sci Rep
Main Authors: Diao, Na, Zhang, Yao, Chen, Keqiang, Yuan, Ruoxi, Lee, Christina, Geng, Shuo, Kowalski, Elizabeth, Guo, Wen, Xiong, Huabao, Li, Mingsong, Li, Liwu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050405/
https://ncbi.nlm.nih.gov/pubmed/27703259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34672
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