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Subclinical dose endotoxin sustains low-grade inflammation and exacerbates steatohepatitis in high-fat diet fed mice

Subclinical circulating bacterial endotoxin lipopolysaccharide (LPS) has been implicated as an important cofactor in the development and progression of nonalcoholic steatohepatitis (NASH), but the underlying mechanisms remain unclear. Here, we demonstrated that 4-week injection with super-low dose L...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Guo, Honghui, Diao, Na, Yuan, Ruoxi, Chen, Keqiang, Geng, Shuo, Li, Mingsong, Li, Liwu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761480/
https://ncbi.nlm.nih.gov/pubmed/26810228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500130
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