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Subclinical dose endotoxin sustains low-grade inflammation and exacerbates steatohepatitis in high-fat diet fed mice

Subclinical circulating bacterial endotoxin lipopolysaccharide (LPS) has been implicated as an important cofactor in the development and progression of nonalcoholic steatohepatitis (NASH), but the underlying mechanisms remain unclear. Here, we demonstrated that 4-week injection with super-low dose L...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Guo, Honghui, Diao, Na, Yuan, Ruoxi, Chen, Keqiang, Geng, Shuo, Li, Mingsong, Li, Liwu
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761480/
https://ncbi.nlm.nih.gov/pubmed/26810228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500130
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